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Reversal of homocysteine-induced neurotoxicity in rat hippocampal neurons by astaxanthin: evidences for mitochondrial dysfunction and signaling crosstalk

Elevated plasma level of homocysteine (Hcy) represents an independent risk for neurological diseases, and induction of oxidative damage is considered as one of the most important pathomechanisms. Astaxanthin (ATX) exhibits strong antioxidant activity in kinds of experimental models. However, the pot...

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Detalles Bibliográficos
Autores principales: Wang, Xian-jun, Chen, Wang, Fu, Xiao-ting, Ma, Jin-kui, Wang, Mei-hong, Hou, Ya-jun, Tian, Da-chen, Fu, Xiao-yan, Fan, Cun-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197197/
https://www.ncbi.nlm.nih.gov/pubmed/30374413
http://dx.doi.org/10.1038/s41420-018-0114-x