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Predicting the need for a reduced drug dose, at first prescription

Prescribing the right drug with the right dose is a central tenet of precision medicine. We examined the use of patients’ prior Electronic Health Records to predict a reduction in drug dosage. We focus on drugs that interact with the P450 enzyme family, because their dosage is known to be sensitive...

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Detalles Bibliográficos
Autores principales: Coulet, Adrien, Shah, Nigam H., Wack, Maxime, Chawki, Mohammad B., Jay, Nicolas, Dumontier, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197198/
https://www.ncbi.nlm.nih.gov/pubmed/30349060
http://dx.doi.org/10.1038/s41598-018-33980-0