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Predicting the need for a reduced drug dose, at first prescription
Prescribing the right drug with the right dose is a central tenet of precision medicine. We examined the use of patients’ prior Electronic Health Records to predict a reduction in drug dosage. We focus on drugs that interact with the P450 enzyme family, because their dosage is known to be sensitive...
Autores principales: | Coulet, Adrien, Shah, Nigam H., Wack, Maxime, Chawki, Mohammad B., Jay, Nicolas, Dumontier, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197198/ https://www.ncbi.nlm.nih.gov/pubmed/30349060 http://dx.doi.org/10.1038/s41598-018-33980-0 |
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