Melatonin suppresses TLR9-triggered proinflammatory cytokine production in macrophages by inhibiting ERK1/2 and AKT activation

Toll-like receptor (TLR) signaling plays major roles in innate immune response in macrophages. Melatonin regulates TLR3- and TLR4-mediated innate immune responses in macrophages. However, it remains unknown whether melatonin regulates TLR9-mediated innate immune responses in macrophages. Here we dem...

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Detalles Bibliográficos
Autores principales: Xu, Xiongfei, Wang, Guoquan, Ai, Lingling, Shi, Jianhui, Zhang, Jing, Chen, Yu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197220/
https://www.ncbi.nlm.nih.gov/pubmed/30349079
http://dx.doi.org/10.1038/s41598-018-34011-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197220/
https://www.ncbi.nlm.nih.gov/pubmed/30349079
http://dx.doi.org/10.1038/s41598-018-34011-8

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