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Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

The associations of single nucleotide polymorphisms (SNPs) in PLA2R1 and HLA-DQA1, as well as HLA-DRB1*15:01-DQB1*06:02 haplotype with idiopathic membranous nephropathy (IMN) is well known. However, the primary associations of these loci still need to be determined. We used Japanese-specific SNP gen...

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Detalles Bibliográficos
Autores principales: Latt, Khun Zaw, Honda, Kenjiro, Thiri, Myo, Hitomi, Yuki, Omae, Yosuke, Sawai, Hiromi, Kawai, Yosuke, Teraguchi, Shunsuke, Ueno, Kazuko, Nagasaki, Masao, Mabuchi, Akihiko, Kaga, Hajime, Komatsuda, Atsushi, Tokunaga, Katsushi, Noiri, Eisei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197221/
https://www.ncbi.nlm.nih.gov/pubmed/30349113
http://dx.doi.org/10.1038/s41598-018-33612-7