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Altered hippocampal gene expression and structure in transgenic mice overexpressing neuregulin 1 (Nrg1) type I

Transgenic mice overexpressing the type I isoform of neuregulin 1 (Nrg1; NRG1) have alterations in hippocampal gamma oscillations and an age-emergent deficit in hippocampus-dependent spatial working memory. Here, we examined the molecular and morphological correlates of these findings. Microarrays s...

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Detalles Bibliográficos
Autores principales: Deakin, Inga H., Godlewska, Beata R., Walker, Mary A., Huang, Guo-Jen, Schwab, Markus H., Nave, Klaus-Armin, Law, Amanda J., Harrison, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197224/
https://www.ncbi.nlm.nih.gov/pubmed/30348978
http://dx.doi.org/10.1038/s41398-018-0288-2