A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage

Cartilage provides low-friction properties and plays an essential role in diarthrodial joints. A hydrated ground substance composed mainly of proteoglycans (PGs) and a fibrillar collagen network are the main constituents of cartilage. Unfortunately, traumatic joint loading can destroy this complex s...

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Detalles Bibliográficos
Autores principales: Orozco, Gustavo A., Tanska, Petri, Florea, Cristina, Grodzinsky, Alan J., Korhonen, Rami K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197240/
https://www.ncbi.nlm.nih.gov/pubmed/30348953
http://dx.doi.org/10.1038/s41598-018-33759-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197240/
https://www.ncbi.nlm.nih.gov/pubmed/30348953
http://dx.doi.org/10.1038/s41598-018-33759-3

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