Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling

The Hippo pathway is involved in intestinal epithelial homeostasis with Wnt, BMP, Notch, and EGF signaling. We investigated the relationship between Hippo and other signaling pathways and the role of MOB kinase activator 1A/1B (MOB1A/B) in intestinal homeostasis. Mice with intestinal epithelial cell...

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Detalles Bibliográficos
Autores principales: Bae, June Sung, Jeon, Yoon, Kim, Sun Mi, Jang, Ji Yun, Park, Mi Kyung, Kim, In-Hoo, Hwang, Deog Su, Lim, Dae-Sik, Lee, Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197243/
https://www.ncbi.nlm.nih.gov/pubmed/30349003
http://dx.doi.org/10.1038/s41419-018-1138-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197243/
https://www.ncbi.nlm.nih.gov/pubmed/30349003
http://dx.doi.org/10.1038/s41419-018-1138-0

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