Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation

Mitochondrial dysfunction is a frequent participant in common diseases and a principal suspect in aging. To combat mitochondrial dysfunction, eukaryotes have evolved a large repertoire of quality control mechanisms. One such mechanism involves the selective degradation of damaged or misfolded mitoch...

Descripción completa

Detalles Bibliográficos
Autores principales: Pareek, Gautam, Thomas, Ruth E., Vincow, Evelyn S., Morris, David R., Pallanck, Leo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197249/
https://www.ncbi.nlm.nih.gov/pubmed/30374414
http://dx.doi.org/10.1038/s41420-018-0110-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197249/
https://www.ncbi.nlm.nih.gov/pubmed/30374414
http://dx.doi.org/10.1038/s41420-018-0110-1

Ejemplares similares