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Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation

Mitochondrial dysfunction is a frequent participant in common diseases and a principal suspect in aging. To combat mitochondrial dysfunction, eukaryotes have evolved a large repertoire of quality control mechanisms. One such mechanism involves the selective degradation of damaged or misfolded mitoch...

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Detalles Bibliográficos
Autores principales:	Pareek, Gautam, Thomas, Ruth E., Vincow, Evelyn S., Morris, David R., Pallanck, Leo J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197249/ https://www.ncbi.nlm.nih.gov/pubmed/30374414 http://dx.doi.org/10.1038/s41420-018-0110-1

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