Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism

Pseudoaldosteronism is a common adverse effect associated with traditional Japanese Kampo medicines. The pathogenesis is mainly caused by 3-monoglucuronyl glycyrrhetinic acid (3MGA), one of the metabolites of glycyrrhizin (GL) contained in licorice. We developed an anti-3MGA monoclonal antibody (MAb...

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Detalles Bibliográficos
Autores principales: Morinaga, Osamu, Ishiuchi, Kan’ichiro, Ohkita, Takeshi, Tian, Chuanting, Hirasawa, Asuka, Mitamura, Miaki, Maki, Yasuhito, Yasujima, Tomoya, Yuasa, Hiroaki, Makino, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197257/
https://www.ncbi.nlm.nih.gov/pubmed/30348944
http://dx.doi.org/10.1038/s41598-018-33834-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197257/
https://www.ncbi.nlm.nih.gov/pubmed/30348944
http://dx.doi.org/10.1038/s41598-018-33834-9

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