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Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism
Pseudoaldosteronism is a common adverse effect associated with traditional Japanese Kampo medicines. The pathogenesis is mainly caused by 3-monoglucuronyl glycyrrhetinic acid (3MGA), one of the metabolites of glycyrrhizin (GL) contained in licorice. We developed an anti-3MGA monoclonal antibody (MAb...
Autores principales: | Morinaga, Osamu, Ishiuchi, Kan’ichiro, Ohkita, Takeshi, Tian, Chuanting, Hirasawa, Asuka, Mitamura, Miaki, Maki, Yasuhito, Yasujima, Tomoya, Yuasa, Hiroaki, Makino, Toshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197257/ https://www.ncbi.nlm.nih.gov/pubmed/30348944 http://dx.doi.org/10.1038/s41598-018-33834-9 |
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