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eLD: entropy-based linkage disequilibrium index between multiallelic sites
Quantification of linkage disequilibrium (LD) is a critical step in studies investigating human genome variations. Commonly used LD indices such as r(2) handle LD of biallelic variants for two sites. As shown in a previously introduced LD index of ε, normalized entropy difference of the haplotype fr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197273/ https://www.ncbi.nlm.nih.gov/pubmed/30374405 http://dx.doi.org/10.1038/s41439-018-0030-x |