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Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7

Protein tyrosine kinase 7 (PTK7) and cancer-associated fibroblasts (CAFs) play important roles in cancer stemness, respectively. However, little is known about interaction between CAFs and PTK7 in cancers. In this study, we showed that PTK7 was significantly correlated with the Wnt/β-Catenin pathway...

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Detalles Bibliográficos
Autores principales: Yu, Binbin, Wu, Kailiu, Wang, Xu, Zhang, Jianjun, Wang, Lizhen, Jiang, Yingying, Zhu, Xueqin, Chen, Wantao, Yan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197282/
https://www.ncbi.nlm.nih.gov/pubmed/30348980
http://dx.doi.org/10.1038/s41419-018-1116-6