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Oncolytic Virus-Mediated RAS Targeting in Rhabdomyosarcoma

Aberrant activation of the receptor tyrosine kinase-mediated RAS signaling cascade is the primary driver of embryonal rhabdomyosarcoma (ERMS), a pediatric cancer characterized by a block in myogenic differentiation. To investigate the cellular function of activated RAS signaling in regulating the gr...

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Detalles Bibliográficos
Autores principales: Phelps, Michael P., Yang, Heechang, Patel, Shivani, Rahman, Masmudur M., McFadden, Grant, Chen, Eleanor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197336/
https://www.ncbi.nlm.nih.gov/pubmed/30364635
http://dx.doi.org/10.1016/j.omto.2018.09.001