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Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

BACKGROUND: Celastrol is an active ingredient of Chinese medicine Tripterygium wilfordii which is clinically used to treat the immune diseases. Currently, celastrol is documented as a potent agent for treating cancer and inflammatory disorders. This study was to investigate the effect of celastrol o...

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Detalles Bibliográficos
Autores principales: Yu, Xiaowen, Meng, Xia, Xu, Man, Zhang, Xuejuan, Zhang, Yue, Ding, Guixia, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197337/
https://www.ncbi.nlm.nih.gov/pubmed/30268831
http://dx.doi.org/10.1016/j.ebiom.2018.09.031