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Sildenafil improves blood perfusion in steroid-induced avascular necrosis of femoral head in rabbits via a protein kinase G-dependent mechanism

OBJECTIVE: The aim of the study were to evaluate the effect of sildenafil against avascular necrosis of femoral head (ANFH) in a rabbit model, and to study the role of protein kinase G (PKG) pathway and vascular endothelial growth factor (VEGF) in ANFH. METHODS: Three weeks after inducing ANFH with...

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Detalles Bibliográficos
Autores principales: Song, Qichun, Ni, Jianlong, Jiang, Hongyuan, Shi, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Association of Orthopaedics and Traumatology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197368/
https://www.ncbi.nlm.nih.gov/pubmed/28774681
http://dx.doi.org/10.1016/j.aott.2017.07.002