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PRMT1 Deficiency in Mouse Juvenile Heart Induces Dilated Cardiomyopathy and Reveals Cryptic Alternative Splicing Products

Protein arginine methyltransferase 1 (PRMT1) catalyzes the asymmetric dimethylation of arginine residues in proteins and methylation of various RNA-binding proteins and is associated with alternative splicing in vitro. Although PRMT1 has essential in vivo roles in embryonic development, CNS developm...

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Detalles Bibliográficos
Autores principales: Murata, Kazuya, Lu, Weizhe, Hashimoto, Misuzu, Ono, Natsumi, Muratani, Masafumi, Nishikata, Kana, Kim, Jun-Dal, Ebihara, Shizufumi, Ishida, Junji, Fukamizu, Akiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197527/
https://www.ncbi.nlm.nih.gov/pubmed/30321814
http://dx.doi.org/10.1016/j.isci.2018.09.023