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Cells respond to deletion of CAV1 by increasing synthesis of extracellular matrix

A range of cellular functions have been attributed to caveolae, flask-like invaginations of the plasma membrane. Here, we have used RNA-seq to achieve quantitative transcriptional profiling of primary embryonic fibroblasts from caveolin 1 knockout mice (CAV1-/- MEFs), and thereby to gain hypothesis-...

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Detalles Bibliográficos
Autores principales: Mendoza-Topaz, C., Nelson, G., Howard, G., Hafner, S., Rademacher, P., Frick, M., Nichols, B. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197626/
https://www.ncbi.nlm.nih.gov/pubmed/30346954
http://dx.doi.org/10.1371/journal.pone.0205306