A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

BACKGROUND: Miltefosine has been used successfully to treat visceral leishmaniasis (VL) in India, but it was unsuccessful for VL in a clinical trial in Brazil. METHODS: To identify molecular markers that predict VL treatment failure whole genome sequencing of 26 L. infantum isolates, from cured and...

Descripción completa

Detalles Bibliográficos
Autores principales: Carnielli, Juliana B.T., Crouch, Kathryn, Forrester, Sarah, Silva, Vladimir Costa, Carvalho, Sílvio F.G., Damasceno, Jeziel D., Brown, Elaine, Dickens, Nicholas J., Costa, Dorcas L., Costa, Carlos H.N., Dietze, Reynaldo, Jeffares, Daniel C., Mottram, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197651/
https://www.ncbi.nlm.nih.gov/pubmed/30268832
http://dx.doi.org/10.1016/j.ebiom.2018.09.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197651/
https://www.ncbi.nlm.nih.gov/pubmed/30268832
http://dx.doi.org/10.1016/j.ebiom.2018.09.029

Ejemplares similares