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Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition

Psychiatric illnesses are complex and polygenic. They are associated with widespread alterations in the brain, which are partly influenced by genetic factors. There have been some attempts to relate polygenic risk scores (PRS) – a measure of the overall genetic risk an individual carries for a disor...

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Detalles Bibliográficos
Autores principales: Ranlund, Siri, Rosa, Maria Joao, de Jong, Simone, Cole, James H., Kyriakopoulos, Marinos, Fu, Cynthia H.Y., Mehta, Mitul A., Dima, Danai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197704/
https://www.ncbi.nlm.nih.gov/pubmed/30340201
http://dx.doi.org/10.1016/j.nicl.2018.10.008