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Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p

BACKGROUND: Cancer-associated fibroblasts (CAFs) play an important role in regulating tumor progression by transferring exosomes to neighboring cells. Our aim was to clarify the role of microRNA encapsulated in the exosomes derived from CAFs in oral squamous cell carcinoma (OSCC). METHODS: We examin...

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Detalles Bibliográficos
Autores principales: Li, Yao-yin, Tao, Yi-wei, Gao, Shuo, Li, Pei, Zheng, Jian-mao, Zhang, Si-en, Liang, Jianfeng, Zhang, Yuejiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197737/
https://www.ncbi.nlm.nih.gov/pubmed/30243489
http://dx.doi.org/10.1016/j.ebiom.2018.09.006