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Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome

BACKGROUND: Disordered folliculogenesis is a key feature of polycystic ovary syndrome (PCOS), but the underlying molecular mechanism remains unclear. METHODS: Long non-coding RNA (lncRNA) expression in luteinized granulosa cells (hLGCs) derived from women with and without PCOS were analyzed using mi...

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Detalles Bibliográficos
Autores principales: Zhao, Jun, Xu, Jieying, Wang, Wangshen, Zhao, Han, Liu, Hongbin, Liu, Xiaojing, Liu, Jiansheng, Sun, Yun, Dunaif, Andrea, Du, Yanzhi, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197751/
https://www.ncbi.nlm.nih.gov/pubmed/30293818
http://dx.doi.org/10.1016/j.ebiom.2018.09.043