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Centromeres License the Mitotic Condensation of Yeast Chromosome Arms

During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, we show that, unlike wild-type yeast chromosomes, non-chromosomal DNA circles and chromosomes lacking a centromere fail to condense during mitosis. The c...

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Detalles Bibliográficos
Autores principales: Kruitwagen, Tom, Chymkowitch, Pierre, Denoth-Lippuner, Annina, Enserink, Jorrit, Barral, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197839/
https://www.ncbi.nlm.nih.gov/pubmed/30318142
http://dx.doi.org/10.1016/j.cell.2018.09.012