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Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, we show that, unlike wild-type yeast chromosomes, non-chromosomal DNA circles and chromosomes lacking a centromere fail to condense during mitosis. The c...
Autores principales: | Kruitwagen, Tom, Chymkowitch, Pierre, Denoth-Lippuner, Annina, Enserink, Jorrit, Barral, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197839/ https://www.ncbi.nlm.nih.gov/pubmed/30318142 http://dx.doi.org/10.1016/j.cell.2018.09.012 |
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