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Diallyl Trisulfide Suppresses the Production of Lipopolysaccharide-induced Inflammatory Mediators in BV2 Microglia by Decreasing the NF-κB Pathway Activity Associated With Toll-like Receptor 4 and CXCL12/CXCR4 Pathway Blockade

BACKGROUND: Diallyl trisulfide (DATS), a garlic-derived organosulfuric compound, has been documented for potential anti-inflammatory effects. However, the mechanism in microglia remains unknown. In this study, we investigated the anti-inflammatory effects of DATS in lipopolysaccharide (LPS)-stimulat...

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Detalles Bibliográficos
Autores principales: Lee, Hye Hyeon, Jeong, Jin-Woo, Hong, Su Hyun, Park, Cheol, Kim, Byung Woo, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197846/
https://www.ncbi.nlm.nih.gov/pubmed/30370258
http://dx.doi.org/10.15430/JCP.2018.23.3.134