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Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand

T-box riboswitches are cis-regulatory RNA elements that regulate the expression of proteins involved in amino acid biosynthesis and transport by binding to specific tRNAs and sensing their aminoacylation state. While the T-box modular structural elements that recognize different parts of a tRNA have...

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Detalles Bibliográficos
Autores principales: Zhang, Jiacheng, Chetnani, Bhaskar, Cormack, Eric D, Alonso, Dulce, Liu, Wei, Mondragón, Alfonso, Fei, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197855/
https://www.ncbi.nlm.nih.gov/pubmed/30251626
http://dx.doi.org/10.7554/eLife.39518