Structure of the human epithelial sodium channel by cryo-electron microscopy

The epithelial sodium channel (ENaC), a member of the ENaC/DEG superfamily, regulates Na(+) and water homeostasis. ENaCs assemble as heterotrimeric channels that harbor protease-sensitive domains critical for gating the channel. Here, we present the structure of human ENaC in the uncleaved state det...

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Detalles Bibliográficos
Autores principales: Noreng, Sigrid, Bharadwaj, Arpita, Posert, Richard, Yoshioka, Craig, Baconguis, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197857/
https://www.ncbi.nlm.nih.gov/pubmed/30251954
http://dx.doi.org/10.7554/eLife.39340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197857/
https://www.ncbi.nlm.nih.gov/pubmed/30251954
http://dx.doi.org/10.7554/eLife.39340

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