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Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli

Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. However, very little is known about the underlying mechanisms that initiate and modulate the associated protein aggregation and deposition. Model systems have been established to investigate these disease-associa...

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Detalles Bibliográficos
Autores principales: Hand, Kieran, Wilkinson, Mark C., Madine, Jillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197867/
https://www.ncbi.nlm.nih.gov/pubmed/30347409
http://dx.doi.org/10.1371/journal.pone.0206167