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Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli
Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. However, very little is known about the underlying mechanisms that initiate and modulate the associated protein aggregation and deposition. Model systems have been established to investigate these disease-associa...
Autores principales: | Hand, Kieran, Wilkinson, Mark C., Madine, Jillian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197867/ https://www.ncbi.nlm.nih.gov/pubmed/30347409 http://dx.doi.org/10.1371/journal.pone.0206167 |
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