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Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation

γδ T‐cells perform a wide range of tissue‐ and disease‐specific functions that are dependent on the effector cytokines produced by these cells. However, the aggregate signals required for the development of interferon‐γ (IFNγ) and interleukin‐17 (IL‐17) producing γδ T‐cells remain unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Zarin, Payam, In, Tracy SH, Chen, Edward LY, Singh, Jastaranpreet, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Anderson, Michele K, Zúñiga‐Pflücker, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197911/
https://www.ncbi.nlm.nih.gov/pubmed/29754419
http://dx.doi.org/10.1111/imcb.12164