Cargando…

Presence of Infected Gr-1(int)CD11b(hi)CD11c(int) Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice

Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunomodulatory function. To study the mechanism by which MDSC affect antimicrobial immunity, we infected mice with two M. avium strains of differential virulence, highly virulent Mycobacterium avium subsp. avium strain 25291 (...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdissa, Ketema, Nerlich, Andreas, Beineke, Andreas, Ruangkiattikul, Nanthapon, Pawar, Vinay, Heise, Ulrike, Janze, Nina, Falk, Christine, Bruder, Dunja, Schleicher, Ulrike, Bogdan, Christian, Weiss, Siegfried, Goethe, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198055/
https://www.ncbi.nlm.nih.gov/pubmed/30386330
http://dx.doi.org/10.3389/fimmu.2018.02317