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Presence of Infected Gr-1(int)CD11b(hi)CD11c(int) Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice
Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunomodulatory function. To study the mechanism by which MDSC affect antimicrobial immunity, we infected mice with two M. avium strains of differential virulence, highly virulent Mycobacterium avium subsp. avium strain 25291 (...
Autores principales: | Abdissa, Ketema, Nerlich, Andreas, Beineke, Andreas, Ruangkiattikul, Nanthapon, Pawar, Vinay, Heise, Ulrike, Janze, Nina, Falk, Christine, Bruder, Dunja, Schleicher, Ulrike, Bogdan, Christian, Weiss, Siegfried, Goethe, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198055/ https://www.ncbi.nlm.nih.gov/pubmed/30386330 http://dx.doi.org/10.3389/fimmu.2018.02317 |
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