Cargando…

Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition

Monoclonal antibodies are playing an increasing role in both human and animal health. Different strategies of protein and chemical engineering, including humanization techniques of non-human antibodies were applied successfully to optimize clinical performances of antibodies. Despite the emergence o...

Descripción completa

Detalles Bibliográficos
Autores principales: Dondelinger, Mathieu, Filée, Patrice, Sauvage, Eric, Quinting, Birgit, Muyldermans, Serge, Galleni, Moreno, Vandevenne, Marylène S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198058/
https://www.ncbi.nlm.nih.gov/pubmed/30386328
http://dx.doi.org/10.3389/fimmu.2018.02278