Discovery of a Novel Na(v)1.7 Inhibitor From Cyriopagopus albostriatus Venom With Potent Analgesic Efficacy

Spider venoms contain a vast array of bioactive peptides targeting ion channels. A large number of peptides have high potency and selectivity toward sodium channels. Na(v)1.7 contributes to action potential generation and propagation and participates in pain signaling pathway. In this study, we desc...

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Detalles Bibliográficos
Autores principales: Zhang, Yunxiao, Peng, Dezheng, Huang, Biao, Yang, Qiuchu, Zhang, Qingfeng, Chen, Minzhi, Rong, Mingqiang, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198068/
https://www.ncbi.nlm.nih.gov/pubmed/30386239
http://dx.doi.org/10.3389/fphar.2018.01158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198068/
https://www.ncbi.nlm.nih.gov/pubmed/30386239
http://dx.doi.org/10.3389/fphar.2018.01158

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