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Discovery of a Novel Na(v)1.7 Inhibitor From Cyriopagopus albostriatus Venom With Potent Analgesic Efficacy
Spider venoms contain a vast array of bioactive peptides targeting ion channels. A large number of peptides have high potency and selectivity toward sodium channels. Na(v)1.7 contributes to action potential generation and propagation and participates in pain signaling pathway. In this study, we desc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198068/ https://www.ncbi.nlm.nih.gov/pubmed/30386239 http://dx.doi.org/10.3389/fphar.2018.01158 |