Force‐frequency relationship and early relaxation kinetics are preserved upon sarcoplasmic blockade in human myocardium

In this study, we investigated the quantitative and qualitative role of the sarcoplasmic reticulum (SR) in the regulation of the force‐frequency relationship (FFR). We blocked the function of SR with cyclopiazonic acid (CPA) and ryanodine and measured twitch kinetics and developed force at various s...

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Detalles Bibliográficos
Autores principales: Chung, Jae‐Hoon, Canan, Benjamin D., Whitson, Bryan A., Kilic, Ahmet, Janssen, Paul M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198135/
https://www.ncbi.nlm.nih.gov/pubmed/30350481
http://dx.doi.org/10.14814/phy2.13898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198135/
https://www.ncbi.nlm.nih.gov/pubmed/30350481
http://dx.doi.org/10.14814/phy2.13898

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