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Bioinformatic data processing pipelines in support of next‐generation sequencing‐based HIV drug resistance testing: the Winnipeg Consensus

INTRODUCTION: Next‐generation sequencing (NGS) has several advantages over conventional Sanger sequencing for HIV drug resistance (HIVDR) genotyping, including detection and quantitation of low‐abundance variants bearing drug resistance mutations (DRMs). However, the high HIV genomic diversity, unpr...

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Detalles Bibliográficos
Autores principales: Ji, Hezhao, Enns, Eric, Brumme, Chanson J., Parkin, Neil, Howison, Mark, Lee, Emma R., Capina, Rupert, Marinier, Eric, Avila‐Rios, Santiago, Sandstrom, Paul, Van Domselaar, Gary, Harrigan, Richard, Paredes, Roger, Kantor, Rami, Noguera‐Julian, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198166/
https://www.ncbi.nlm.nih.gov/pubmed/30350345
http://dx.doi.org/10.1002/jia2.25193