Novel therapeutic roles of MC‐4 in combination with everolimus against advanced renal cell carcinoma by dual targeting of Akt/pyruvate kinase muscle isozyme M2 and mechanistic target of rapamycin complex 1 pathways

Current clinical trials of new anticancer therapies against metastatic renal cell carcinoma (RCC), including molecular‐targeted therapies, have not shown promise. The purpose of this study was to preclinically assess the antitumor effects of MC‐4, a partially purified material of Artemisia annua L.,...

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Detalles Bibliográficos
Autores principales: Son, Ji Yeon, Yoon, Sungpil, Tae, In Hwan, Park, Yu Jin, De, Umasankar, Jeon, Yukyoung, Park, Young Ju, Rhyu, Im Joo, Lee, Byung Mu, Chung, Kyu‐Huck, Lim, Joung Eun, Lee, Se Jeong, Lee, Hye Won, Kwak, Jong Hwan, Kim, Hyung Sik, Choi, Han Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198234/
https://www.ncbi.nlm.nih.gov/pubmed/30160042
http://dx.doi.org/10.1002/cam4.1748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198234/
https://www.ncbi.nlm.nih.gov/pubmed/30160042
http://dx.doi.org/10.1002/cam4.1748

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