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Reconstitution of Mammalian Enzymatic Deacylation Reactions in Live Bacteria Using Native Acylated Substrates

[Image: see text] Lysine deacetylases (KDACs) are enzymes that catalyze the hydrolysis of acyl groups from acyl-lysine residues. The recent identification of thousands of putative acylation sites, including specific acetylation sites, created an urgent need for biochemical methodologies aimed at bet...

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Detalles Bibliográficos
Autores principales: Avrahami, Emanuel M., Levi, Shahar, Zajfman, Eyal, Regev, Clil, Ben-David, Oshrit, Arbely, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198279/
https://www.ncbi.nlm.nih.gov/pubmed/30207693
http://dx.doi.org/10.1021/acssynbio.8b00314