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Differential genome-wide profiling of alternative polyadenylation sites in nasopharyngeal carcinoma by high-throughput sequencing

BACKGROUND: Alternative polyadenylation (APA) is a widespread phenomenon in the posttranscriptional regulation of gene expression that generates mRNAs with alternative 3′-untranslated regions (3’UTRs). APA contributes to the pathogenesis of various diseases, including cancer. However, the potential...

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Detalles Bibliográficos
Autores principales: Xu, Ya-Fei, Li, Ying-Qing, Liu, Na, He, Qing-Mei, Tang, Xin-Ran, Wen, Xin, Yang, Xiao-Jing, Sun, Ying, Ma, Jun, Tang, Ling-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198351/
https://www.ncbi.nlm.nih.gov/pubmed/30352587
http://dx.doi.org/10.1186/s12929-018-0477-6