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Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial

BACKGROUND: We assessed the efficacy and safety of avelumab, an anti-programmed death ligand 1 (PD-L1) antibody, in patients with previously treated metastatic adrenocortical carcinoma (mACC). METHODS: In this phase 1b expansion cohort, patients with mACC and prior platinum-based therapy received av...

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Detalles Bibliográficos
Autores principales: Le Tourneau, Christophe, Hoimes, Christopher, Zarwan, Corrine, Wong, Deborah J., Bauer, Sebastian, Claus, Rainer, Wermke, Martin, Hariharan, Subramanian, von Heydebreck, Anja, Kasturi, Vijay, Chand, Vikram, Gulley, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198369/
https://www.ncbi.nlm.nih.gov/pubmed/30348224
http://dx.doi.org/10.1186/s40425-018-0424-9