In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

BACKGROUND: The airways of the majority of adolescent cystic fibrosis (CF) patients are persistently colonized or infected by Staphylococcus aureus. Using whole genome sequencing, we studied the evolutionary traits within a S. aureus population in the airways of a CF patient hypothesizing that horiz...

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Detalles Bibliográficos
Autores principales: Langhanki, Lars, Berger, Petya, Treffon, Janina, Catania, Francesco, Kahl, Barbara C., Mellmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198438/
https://www.ncbi.nlm.nih.gov/pubmed/30348081
http://dx.doi.org/10.1186/s12866-018-1308-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198438/
https://www.ncbi.nlm.nih.gov/pubmed/30348081
http://dx.doi.org/10.1186/s12866-018-1308-3

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