PKM2 is not required for pancreatic ductal adenocarcinoma

BACKGROUND: While most cancer cells preferentially express the M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2), PKM2 is dispensable for tumor development in several mouse cancer models. PKM2 is expressed in human pancreatic cancer, and there have been conflicting reports on the associatio...

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Detalles Bibliográficos
Autores principales: Hillis, Alissandra L, Lau, Allison N, Devoe, Camille X, Dayton, Talya L, Danai, Laura V, Di Vizio, Dolores, Vander Heiden, Matthew G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198443/
https://www.ncbi.nlm.nih.gov/pubmed/30386596
http://dx.doi.org/10.1186/s40170-018-0188-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198443/
https://www.ncbi.nlm.nih.gov/pubmed/30386596
http://dx.doi.org/10.1186/s40170-018-0188-1

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