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Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours

BACKGROUND: Circadian rhythms maintain tissue homeostasis during the 24-h day-night cycle. Cell-autonomous circadian clocks play fundamental roles in cell division, DNA damage responses and metabolism. Circadian disruptions have been proposed as a contributing factor for cancer initiation and progre...

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Detalles Bibliográficos
Autores principales: Broadberry, Eleanor, McConnell, James, Williams, Jack, Yang, Nan, Zindy, Egor, Leek, Angela, Waddington, Rachel, Joseph, Leena, Howe, Miles, Meng, Qing-Jun, Streuli, Charles H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198506/
https://www.ncbi.nlm.nih.gov/pubmed/30348208
http://dx.doi.org/10.1186/s13058-018-1053-4