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Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines

BACKGROUND: Although metastasis is ultimately responsible for about 90% of breast cancer mortality, the vast majority of breast-cancer-related deaths are due to progressive recurrences from non-metastatic disease. Current adjuvant therapies are unable to prevent progressive recurrences for a signifi...

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Detalles Bibliográficos
Autores principales: Ravindranathan, Sruthi, Nguyen, Khue G., Kurtz, Samantha L., Frazier, Haven N., Smith, Sean G., Koppolu, Bhanu prasanth, Rajaram, Narasimhan, Zaharoff, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198508/
https://www.ncbi.nlm.nih.gov/pubmed/30348199
http://dx.doi.org/10.1186/s13058-018-1054-3