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Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells

BACKGROUND: The dismal prognosis of patients with glioblastoma (GBM) is attributed to a rare subset of cancer stem cells that display characteristics of tumor initiation, growth, and resistance to aggressive treatment involving chemotherapy and concomitant radiation. Recent research on the substanti...

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Detalles Bibliográficos
Autores principales: Tung, Brian, Ma, Ding, Wang, Shuyan, Oyinlade, Olutobi, Laterra, John, Ying, Mingyao, Lv, Sheng-Qing, Wei, Shuang, Xia, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198521/
https://www.ncbi.nlm.nih.gov/pubmed/30348136
http://dx.doi.org/10.1186/s12885-018-4874-8