Genotype effects contribute to variation in longitudinal methylome patterns in older people

BACKGROUND: DNA methylation levels change along with age, but few studies have examined the variation in the rate of such changes between individuals. METHODS: We performed a longitudinal analysis to quantify the variation in the rate of change of DNA methylation between individuals using whole bloo...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Marioni, Riccardo E, Robinson, Matthew R, Higham, Jon, Sproul, Duncan, Wray, Naomi R, Deary, Ian J, McRae, Allan F, Visscher, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198530/
https://www.ncbi.nlm.nih.gov/pubmed/30348214
http://dx.doi.org/10.1186/s13073-018-0585-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198530/
https://www.ncbi.nlm.nih.gov/pubmed/30348214
http://dx.doi.org/10.1186/s13073-018-0585-7

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