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From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology

Patients with inflammatory bowel disease have an increased risk of developing colorectal cancer, and this risk is related to disease duration, extent, and cumulative inflammation burden. Carcinogenesis follows the principles of Darwinian evolution, whereby somatic cells acquire genomic alterations t...

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Detalles Bibliográficos
Autores principales: Al Bakir, Ibrahim, Curtius, Kit, Graham, Trevor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198656/
https://www.ncbi.nlm.nih.gov/pubmed/30386335
http://dx.doi.org/10.3389/fimmu.2018.02368