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From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology
Patients with inflammatory bowel disease have an increased risk of developing colorectal cancer, and this risk is related to disease duration, extent, and cumulative inflammation burden. Carcinogenesis follows the principles of Darwinian evolution, whereby somatic cells acquire genomic alterations t...
Autores principales: | Al Bakir, Ibrahim, Curtius, Kit, Graham, Trevor A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198656/ https://www.ncbi.nlm.nih.gov/pubmed/30386335 http://dx.doi.org/10.3389/fimmu.2018.02368 |
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